Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups
Abstract Atypical teratoid rhabdoid tumors (ATRT) are divided into MYC, TYR and SHH subgroups, suggesting diverse lineages of origin.Here, we investigate the imaging of human ATRT at diagnosis and the precise anatomic origin of brain tumors in stirrup extender western the Rosa26-CreERT2::Smarcb1flox/flox model.This cross-species analysis points to